Best for Large Dogs: WHIMZEES Brushzees Natural Daily Dental Dog Treats

If you have a larger pooch, you’ll want a treat that’s just larger than your dog’s mouth—and these are perfect for dogs that are 40 pounds and up. Not only are they a great way to reward your pup, but they are also designed with hollow shapes and spaces to get into the hard-to-reach places between your pup’s teeth (kind of like flossing) and clean them. They also feature knobs that help boost blood flow to the bum and prevent tartar build-up. But WHIMZEES aren’t just good for your pooch’s teeth; they’re essentially a multivitamin with added antioxidants and fiber to keep your best friend in tip-top shape.

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